It's the "Snakes on a Plane" sequel -- "Snakes on an 'Extra' Junket"!

As "Extra's" Terri Seymour chatted up "Grown Ups" stars Salma Hayek, Maria Bello and Maya Rudolph, they got an expected guest -- a harmless but rather large snake --- which sent the girls into a tizzy, as they scrambled to get away from the reptile, especially the frantic, screaming Salma.

"It was like a python. It was thick. Its head was like this like a cobra!" Bello exclaimed afterward.

And what about Salma? "She split. She's on the next plane," Rudolph said. "She's in the hospital," Bello laughed.

Check out the hilarious raw reactions!