Johnny Depp finds himself falling for Angelina Jolie in The Tourist – but the romance may come with a hefty price: his life.

In the new trailer for the action-drama, Jolie's character, Elise, deliberately crosses paths with Frank on a train, an American traveler who has retreated to Europe to mend a broken heart.

He soon finds out – after locking lips and falling for her – that he's now entangled in a case of mistaken identity and has to go on the run.

"You were part of the plan," she tells him. "I'm sorry I got you involved in all of this."

The flick, which Jolie filmed in Paris and in Venice, arrives in theaters Dec. 10.